Fibroblasts are skin cells that generate collagen and elastin fibres, which are essential for the skin’s support and elasticity. Over time they age and function less efficiently resulting in gradual skin aging and the appearance of wrinkles and sagging. Moreover, the cumulative effect of the sun on the skin accelerates biological aging leading to photo-aging, which affects even young people. A typical example is the difference in skin quality between exposed areas, such as face, décolleté, and protected areas, such as chest, of people who are exposed to the sun.

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